Smaug assembles an ATP-dependent stable complex repressingnanosmRNA translation at multiple levels
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چکیده
منابع مشابه
Smaug assembles an ATP-dependent stable complex repressing nanos mRNA translation at multiple levels.
The nanos (nos) mRNA encodes the posterior determinant of the Drosophila embryo. Translation of the RNA is repressed throughout most of the embryo by the protein Smaug binding to Smaug recognition elements (SREs) in the 3' UTR. Translation is locally activated at the posterior pole by Oskar. This paper reports that the SREs govern the time- and ATP-dependent assembly of an exceedingly stable re...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2010
ISSN: 0261-4189
DOI: 10.1038/emboj.2010.283